The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder

نویسندگان

  • Benny Liberg
  • Christoffer Rahm
چکیده

Psychomotor disturbances (PMD) are a classic feature of depressive disorder that provides rich clinical information. The aim our narrative review was to characterize the functional anatomy of PMD by summarizing findings from neuroimaging studies. We found evidence across several neuroimaging modalities that suggest involvement of fronto-striatal neurocircuitry, and monoaminergic pathways and metabolism. We suggest that PMD in major depressive disorder emerge from an alteration of limbic signals, which influence emotion, volition, higher-order cognitive functions, and movement.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Functional and Structural Alterations in the Cingulate Motor Area Relate to Decreased Fronto-Striatal Coupling in Major Depressive Disorder with Psychomotor Disturbances

Psychomotor disturbances are a classic feature of major depressive disorders. These can manifest as lack of facial expressions and decreased speech production, reduced body posture and mobility, and slowed voluntary movement. The neural correlates of psychomotor disturbances in depression are poorly understood but it has been suggested that outputs from the cingulate motor area (CMA) to striata...

متن کامل

The Frequency Distribution of Chief Complaints in Patients with Major Depressive Disorder Referring to Psychiatric Clinics in Kerman

Introduction: Physical symptoms associated with depression and common psychiatric disorders sometimes lead to the misdiagnosis of depressive disorders. The aim of this study was to determine the frequency distribution of different chief complaints in patients with major depressive disorder referring to psychiatric clinics according to their demographic characteristics and source of referral. Me...

متن کامل

Somatic Symptom Scale -8 in Major Depressive Disorder: A Psychometric Evaluation

Objective: Somatic symptom disorder (SSD) is characterized by somatic symptoms that are very distressing or cause considerable functional disability. SSD is associated with various medical and psychiatric conditions and imposes high costs on the patient's health care system. Therefore, diagnosis and treatment of SSD are crucial. The Somatic Symptom Scale-8 (SSS-8) is a valuable and brief self-r...

متن کامل

Psychomotor disturbances in bipolar disorder – investigations using structural and functional neuroimaging

Psychomotor disturbances in bipolar disorder are an expression of alterations in volition, cognition, emotion and motor control. While psychomotor disturbances remain a classic hallmark of severe mood disorders, there is limited knowledge about its mediators and neural correlates. The general aim of this thesis was to obtain a better understanding of psychomotor disturbances in bipolar disorder...

متن کامل

A Comparison of Selective Attention Processing in Major Depressive Disorder and Schizophrenia

Objective: Cognitive deficits play an important role in differential diagnostics, prognosis and rehabilitation of people with psychological disorders. Attention problems have profound impact on the therapeutic response, risk of relapse, function and quality of life in people with major depressive disorder and schizophrenia. This study compared selective attention of people with schizophrenia, M...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2015